Glutamine/proline-rich PQE-1 proteins protect Caenorhabditis elegans neurons from huntingtin polyglutamine neurotoxicity

Huntington's disease is a progressive neurodegenerative disease caused by a polyglutamine (polyQ) repeat expansion in the huntingtin protein [Huntington's Disease Collaborative Research Group (1993) Cell 72, 971–983]. To understand the mechanism by which polyQ repeats cause neurodegeneration and cel...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Faber, Peter W., Voisine, Cindy, King, Daphne C., Bates, Emily A., Hart, Anne C.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2002
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139281/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12486229/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.262544899
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