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Glutamine/proline-rich PQE-1 proteins protect Caenorhabditis elegans neurons from huntingtin polyglutamine neurotoxicity

Huntington's disease is a progressive neurodegenerative disease caused by a polyglutamine (polyQ) repeat expansion in the huntingtin protein [Huntington's Disease Collaborative Research Group (1993) Cell 72, 971–983]. To understand the mechanism by which polyQ repeats cause neurodegenerati...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Faber, Peter W., Voisine, Cindy, King, Daphne C., Bates, Emily A., Hart, Anne C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2002
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC139281/
https://ncbi.nlm.nih.gov/pubmed/12486229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.262544899
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