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Class IA phosphoinositide 3-kinases are obligate p85-p110 heterodimers
Class IA phosphoinositide 3-kinases (PI3Ks) signal downstream of tyrosine kinases and Ras and control a wide variety of biological responses. In mammals, these heterodimeric PI3Ks consist of a p110 catalytic subunit (p110α, p110β, or p110δ) bound to any of five distinct regulatory subunits (p85α, p8...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2007
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1876529/ https://ncbi.nlm.nih.gov/pubmed/17470792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700373104 |
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