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Calpain interacts with class IA phosphoinositide 3-kinases regulating their stability and signaling activity

Class IA phosphoinositide 3-kinases (PI3Ks) are signaling enzymes with key roles in the regulation of essential cellular functions and disease, including cancer. Accordingly, their activity is tightly controlled in cells to maintain homeostasis. The formation of multiprotein complexes is a ubiquitou...

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Detalhes bibliográficos
Main Authors: Beltran, Luisa, Chaussade, Claire, Vanhaesebroeck, Bart, Cutillas, Pedro Rodriguez
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182684/
https://ncbi.nlm.nih.gov/pubmed/21930956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107692108
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