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Calpain interacts with class IA phosphoinositide 3-kinases regulating their stability and signaling activity
Class IA phosphoinositide 3-kinases (PI3Ks) are signaling enzymes with key roles in the regulation of essential cellular functions and disease, including cancer. Accordingly, their activity is tightly controlled in cells to maintain homeostasis. The formation of multiprotein complexes is a ubiquitou...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3182684/ https://ncbi.nlm.nih.gov/pubmed/21930956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107692108 |
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