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T-cell function is partially maintained in the absence of class IA phosphoinositide 3-kinase signaling
The class IA subgroup of phosphoinositide 3-kinase (PI3K) is activated downstream of antigen receptors, costimulatory molecules, and cytokine receptors on lymphocytes. Targeted deletion of individual genes for class IA regulatory subunits severely impairs the development and function of B cells but...
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| Asıl Yazarlar: | , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society of Hematology
2007
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1852227/ https://ncbi.nlm.nih.gov/pubmed/17164340 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-07-038620 |
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