Caricamento...

Oncogenic transformation induced by the p110β, -γ, and -δ isoforms of class I phosphoinositide 3-kinase

Class I phosphoinositide 3-kinase contains four isoforms of the catalytic subunit, p110α, -β, -γ, and -δ. At physiological levels of expression, the wild-type p110α isoform lacks oncogenic potential, but gain-of-function mutations and overexpression of p110α are correlated with oncogenicity. The p11...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Kang, Sohye, Denley, Adam, Vanhaesebroeck, Bart, Vogt, Peter K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2006
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360601/
https://ncbi.nlm.nih.gov/pubmed/16432180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510772103
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !