Randomized cross-over clinical trial to study potential pharmacokinetic interactions between cisplatin or carboplatin and etoposide

AIMS: Cisplatin and carboplatin are often used in combination with etoposide. In a randomized cross-over study, the potential interaction between the two platinum drugs and the metabolism of etoposide was explored. In vitro investigations using human liver microsomes were also performed. METHODS: Et...

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Autors principals: Thomas, Huw D, Porter, David J, Bartelink, Imke, Nobbs, Joy R, Cole, Michael, Elliott, Suzie, Newell, David R, Calvert, A Hilary, Highley, Martin, Boddy, Alan V
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2002
Matèries:
Drug Interaction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874557/
https://ncbi.nlm.nih.gov/pubmed/11849199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.0306-5251.2001.01513.x
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