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The effects of age and renal and hepatic impairment on the pharmacokinetics of sildenafil citrate
AIMS: To investigate the effects of age and renal and hepatic impairment on the pharmacokinetics, tolerability and safety of sildenafil (single 50-mg oral dose) and its major circulating N-desmethyl metabolite, UK-103,320. METHODS: Three open-label, parallel-group studies were conducted. The first s...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1874252/ https://ncbi.nlm.nih.gov/pubmed/11879256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.0306-5251.2001.00029.x |
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