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Comparative human pharmacokinetics and metabolism of single-dose oral and intravenous sildenafil citrate

AIMS: To characterize the absorption, metabolism and excretion of an oral and intravenous (IV) dose of radiolabelled [(14)C]-sildenafil citrate in healthy male subjects. Specific objectives were to measure the cumulative amount of drug-related radiolabelled material excreted in the urine and faeces...

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Hlavní autoři: Muirhead, Gary J, Rance, David J, Walker, Donald K, Wastall, Philip
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874255/
https://ncbi.nlm.nih.gov/pubmed/11879255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.0306-5251.2001.00028.x
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