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Comparative single-dose pharmacokinetics of sildenafil after oral and rectal administration in healthy beagle dogs
BACKGROUND: Sildenafil citrate, a highly selective phosphodiesterase type 5 inhibitor, is used to treat pulmonary hypertension (PH) in veterinary medicine. The objective of this study was to investigate pharmacokinetic profiles by oral administration of orally disintegrating film (ODF) and film coat...
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| Publicado no: | BMC Vet Res |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6154896/ https://ncbi.nlm.nih.gov/pubmed/30249242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12917-018-1617-7 |
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