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Pharmacokinetics of clozapine and its metabolites in psychiatric patients: plasma protein binding and renal clearance
AIMS: N-Desmethylclozapine and clozapine N-oxide are major metabolites of the atypical neuroleptic clozapine in humans and undergo renal excretion. The aim of this study was to investigate to what extent the elimination of these metabolites in urine contributes to the total fate of clozapine in pati...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Blackwell Science Inc
1998
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1873700/ https://ncbi.nlm.nih.gov/pubmed/9833598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1998.00822.x |
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