Genetic Variation Influences the B-Cell Response to Immunization with a Pneumococcal Polysaccharide Conjugate Vaccine

CBA/J mice immunized with pneumococcal 23F-CRM(197) vaccine produce significantly lower titers of 23F-specific antibodies and fewer 23F-specific antibody-secreting cells (ASC) than did BALB/c or (CBA/J × BALB/c)F(1) (CCBAF(1)) mice. The reduced 23F-specific titers of CBA/J versus BALB/c or CCBAF(1)...

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Bibliographische Detailangaben
Hauptverfasser: McCool, T. L., Schreiber, J. R., Greenspan, N. S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Microbial Immunity and Vaccines
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC187339/
https://ncbi.nlm.nih.gov/pubmed/12933893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.9.5402-5406.2003
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