Tumor Necrosis Factor Alpha Is a Key Mediator of Gut Inflammation Seen in Amebic Colitis in Human Intestine in the SCID Mouse-Human Intestinal Xenograft Model of Disease
We used Entamoeba histolytica infection in human intestinal xenografts to study the roles interleukin-1 (IL-1) and tumor necrosis factor alpha (TNF-α) in the pathogenesis of amebic colitis. We found that blockade of TNF-α reduced inflammation and intestinal damage in amebic infection, while inhibiti...
Αποθηκεύτηκε σε:
| Εκδόθηκε σε: | Infect Immun |
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| Κύριοι συγγραφείς: | , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Microbiology (ASM)
2003
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187299/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12933883/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.9.5355-5359.2003 |
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