Shigella Infection in a SCID Mouse-Human Intestinal Xenograft Model: Role for Neutrophils in Containing Bacterial Dissemination in Human Intestine

Shigellae infect human intestine and cause intense inflammation and destruction of colonic and rectal mucosa. To model the interactions of shigella with human intestine in vivo, we have studied shigella infection in human intestinal xenografts in severe combined immunodeficient mice (SCID-HU-INT mic...

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Detalhes bibliográficos
Main Authors: Zhang, Zhi, Jin, Lingling, Champion, Gretchen, Seydel, Karl B., Stanley, Samuel L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98282/
https://ncbi.nlm.nih.gov/pubmed/11292746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.5.3240-3247.2001
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