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Shigella Infection in a SCID Mouse-Human Intestinal Xenograft Model: Role for Neutrophils in Containing Bacterial Dissemination in Human Intestine

Shigellae infect human intestine and cause intense inflammation and destruction of colonic and rectal mucosa. To model the interactions of shigella with human intestine in vivo, we have studied shigella infection in human intestinal xenografts in severe combined immunodeficient mice (SCID-HU-INT mic...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Zhi, Jin, Lingling, Champion, Gretchen, Seydel, Karl B., Stanley, Samuel L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC98282/
https://ncbi.nlm.nih.gov/pubmed/11292746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.5.3240-3247.2001
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