Absence of muscarinic cholinergic airway responses in mice deficient in the cyclic nucleotide phosphodiesterase PDE4D

Muscarinic cholinergic signaling plays an essential role in the control of the normal airway functions and in the development of pulmonary pathologies including asthma. In this paper we demonstrate that the airways of mice deficient in a cAMP-specific phosphodiesterase (PDE4D) are no longer responsi...

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Autores principales: Hansen, Gesine, Jin, S.-L. Catherine, Umetsu, Dale T., Conti, Marco
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2000
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC18727/
https://ncbi.nlm.nih.gov/pubmed/10841571
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