Genetic Evidence in Melanoma and Bladder Cancers that p16 and p53 Function in Separate Pathways of Tumor Suppression

The 9p21 region of human chromosome 9 is a hot spot for chromosomal aberrations in both cultured cell lines and primary tumors. This region contains a gene, P16 (also called MTS1, CDKN2 and p16(INK4)), that encodes a presumptive negative cell cycle regulator called p16. P16 is deleted or mutated at...

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Hlavní autoři: Gruis, Nelleke A., Weaver-Feldhaus, Jane, Liu, Qingyun, Frye, Cheryl, Eeles, Rosalind, Orlow, Irene, Lacombe, Louis, Ponce-Castaneda, Veronica, Lianes, Pilar, Latres, Esther, Skolnick, Mark, Cordon-Cardo, Carlos, Kamb, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: 1995
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Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1869278/
https://ncbi.nlm.nih.gov/pubmed/7747814
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