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Distinct reaction pathway promoted by non-divalent-metal cations in a tertiary stabilized hammerhead ribozyme

Divalent ion sensitivity of hammerhead ribozymes is significantly reduced when the RNA structure includes appropriate tertiary stabilization. Therefore, we investigated the activity of the tertiary stabilized “RzB” hammerhead ribozyme in several nondivalent ions. Ribozyme RzB is active in spermidine...

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Main Authors: Roychowdhury-Saha, Manami, Burke, Donald H.
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory Press 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1869042/
https://ncbi.nlm.nih.gov/pubmed/17456566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.339207
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