טוען...

Conformational heterogeneity and the determinants of tertiary stabilization in the hammerhead ribozyme from Dolichopoda cave crickets

Repetitive DNA elements in Dolichopoda cave cricket genomes contain extended hammerhead ribozymes that are functional in adult crickets, but that exhibit very low self-cleavage activity in vitro relative to other extended hammerhead ribozymes. We find that the parental ribozyme tends to misfold into...

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Main Authors: Roychowdhury-Saha, Manami, Roychowdhury, Sugata, Burke, Donald H
פורמט: Artigo
שפה:Inglês
יצא לאור: Landes Bioscience 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256358/
https://ncbi.nlm.nih.gov/pubmed/21712651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.8.5.16036
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