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The Intracellular Domain of the β2 Subunit Modulates the Gating of Cardiac Na(v)1.5 Channels

We have previously shown that the transmembrane segment plus either the extracellular or intracellular domain of the β1 subunit are required to modify cardiac Na(v)1.5 channels. In this study, we coexpressed the intracellular domain of the β2 subunit in a β1/β2 chimera with Na(v)1.5 channels in Xeno...

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Bibliografski detalji
Glavni autori: Zimmer, Thomas, Benndorf, Klaus
Format: Artigo
Jezik:Inglês
Izdano: Biophysical Society 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868996/
https://ncbi.nlm.nih.gov/pubmed/17369409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.098889
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