Permanent, Lowered HLA Class I Expression Using Lentivirus Vectors With shRNA Constructs: Averting Cytotoxicity by Alloreactive T Lymphocytes

Transplantation of many tissues requires histocompatibility matching of human leukocyte antigens (HLA) to prevent graft rejection, to reduce the level of immunosuppression needed to maintain graft survival, and to minimize the risk of graft-versus-host disease, particularly in the case of bone marro...

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Main Authors: Haga, K., Lemp, N.A., Logg, C.R., Nagashima, J., Faure-Kumar, E., Gomez, G.G., Kruse, C.A., Mendez, R., Stripecke, R., Kasahara, N.A., Cicciarelli, J.C.
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868890/
https://ncbi.nlm.nih.gov/pubmed/17175217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.transproceed.2006.10.158
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