Permanent, Lowered HLA Class I Expression Using Lentivirus Vectors With shRNA Constructs: Averting Cytotoxicity by Alloreactive T Lymphocytes

Transplantation of many tissues requires histocompatibility matching of human leukocyte antigens (HLA) to prevent graft rejection, to reduce the level of immunosuppression needed to maintain graft survival, and to minimize the risk of graft-versus-host disease, particularly in the case of bone marro...

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Autors principals: Haga, K., Lemp, N.A., Logg, C.R., Nagashima, J., Faure-Kumar, E., Gomez, G.G., Kruse, C.A., Mendez, R., Stripecke, R., Kasahara, N.A., Cicciarelli, J.C.
Format: Artigo
Idioma:Inglês
Publicat: 2006
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868890/
https://ncbi.nlm.nih.gov/pubmed/17175217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.transproceed.2006.10.158
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