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KCNJ2 mutations in arrhythmia patients referred for LQT testing: a mutation T305A with novel effect on rectification properties

BACKGROUND: Loss-of-function mutations in the KCNJ2 cause ~50% of Andersen-Tawil Syndrome (ATS) characterized by a classic triad of periodic paralysis, ventricular arrhythmia, and dysmorphic features. Do KCNJ2 mutations occur in patients lacking this triad and lacking a family history of ATS? OBJECT...

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Detalhes bibliográficos
Main Authors: Eckhardt, Lee L., Farley, Amanda L., Rodriguez, Esther, Ruwaldt, Karen, Hammill, Daniel, Tester, David J., Ackerman, Michael J., Makielski, Jonathan C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868697/
https://ncbi.nlm.nih.gov/pubmed/17341397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2006.10.025
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