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Loss-of-Function Mutations in the KCNJ8-Encoded Kir6.1 K(ATP) Channel and Sudden Infant Death Syndrome
BACKGROUND: Approximately 10% of sudden infant death syndrome (SIDS) may stem from cardiac channelopathies. The KCNJ8-encoded Kir6.1 (K(ATP)) channel critically regulates vascular tone and cardiac adaptive response to systemic metabolic stressors, including sepsis. KCNJ8-deficient mice are prone to...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2011
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3281577/ https://ncbi.nlm.nih.gov/pubmed/21836131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.111.960195 |
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