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PKA-Dependent Biophysical Phenotype for V227F-KCNJ2 Mutation in Catecholaminergic Polymorphic Ventricular Tachycardia
BACKGROUND: KCNJ2 encodes Kir2.1, a pore-forming subunit of the cardiac inward rectifier current, I(K1). KCNJ2 mutations are associated with Andersen-Tawil syndrome (ATS) and also Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT). The aim of this study was to characterize the biophysical...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2766080/ https://ncbi.nlm.nih.gov/pubmed/19843922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCEP.109.872309 |
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