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Magnesium Induced Assembly of a Complete DNA Polymerase Catalytic Complex
The molecular details of the nucleotidyl transferase reaction have remained speculative, as strategies to trap catalytic intermediates for structure determination utilize substrates lacking the primer terminus 3’–OH and catalytic Mg(2+) resulting in an incomplete and distorted active site geometry....
में बचाया:
| मुख्य लेखकों: | , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2006
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1868394/ https://ncbi.nlm.nih.gov/pubmed/16615916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2006.01.011 |
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