Characterization of Methylthioadenosin Phosphorylase (MTAP) Expression in Malignant Melanoma

Homozygous deletions of human chromosomal region 9p21 occur frequently in malignant melanoma and are associated with the loss of the tumor suppressor genes p16(INK4a) and p15(INK4b). In the same chromosomal region the methylthioadenosine phosphorylase (MTAP) gene is localized and therefore may also...

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Main Authors: Behrmann, Iris, Wallner, Susanne, Komyod, Waraporn, Heinrich, Peter C., Schuierer, Marion, Buettner, Reinhard, Bosserhoff, Anja-Katrin
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2003
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Regular Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868213/
https://ncbi.nlm.nih.gov/pubmed/12875987
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