Characterization of Methylthioadenosin Phosphorylase (MTAP) Expression in Malignant Melanoma

Homozygous deletions of human chromosomal region 9p21 occur frequently in malignant melanoma and are associated with the loss of the tumor suppressor genes p16(INK4a) and p15(INK4b). In the same chromosomal region the methylthioadenosine phosphorylase (MTAP) gene is localized and therefore may also...

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Detaylı Bibliyografya
Asıl Yazarlar: Behrmann, Iris, Wallner, Susanne, Komyod, Waraporn, Heinrich, Peter C., Schuierer, Marion, Buettner, Reinhard, Bosserhoff, Anja-Katrin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Investigative Pathology 2003
Konular:
Regular Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868213/
https://ncbi.nlm.nih.gov/pubmed/12875987
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