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Simultaneous Detection and Quantification of Mitochondrial DNA Deletion(s), Depletion, and Over-Replication in Patients with Mitochondrial Disease

Heterogeneous clinical expression of mitochondrial DNA (mtDNA) disorders depends on both qualitative and quantitative changes in mtDNA. We developed a sensitive and effective method that simultaneously detects mtDNA deletion(s) and quantifies total mtDNA content. The percentage of deletions and mtDN...

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Detaylı Bibliyografya
Asıl Yazarlar: Bai, Ren-Kui, Wong, Lee-Jun C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Investigative Pathology 2005
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867556/
https://ncbi.nlm.nih.gov/pubmed/16258160
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