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Detection and quantification of mitochondrial DNA deletions from next-generation sequence data
BACKGROUND: Chromosomal deletions represent an important class of human genetic variation. Various methods have been developed to mine “next-generation” sequencing (NGS) data to detect deletions and quantify their clonal abundances. These methods have focused almost exclusively on the nuclear genome...
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| Publicado no: | BMC Bioinformatics |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5657046/ https://ncbi.nlm.nih.gov/pubmed/29072135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1821-7 |
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