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Detection and quantification of mitochondrial DNA deletions from next-generation sequence data

BACKGROUND: Chromosomal deletions represent an important class of human genetic variation. Various methods have been developed to mine “next-generation” sequencing (NGS) data to detect deletions and quantify their clonal abundances. These methods have focused almost exclusively on the nuclear genome...

詳細記述

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書誌詳細
出版年:BMC Bioinformatics
主要な著者: Bosworth, Colleen M., Grandhi, Sneha, Gould, Meetha P., LaFramboise, Thomas
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5657046/
https://ncbi.nlm.nih.gov/pubmed/29072135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1821-7
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