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Single Monochrome Real-Time RT-PCR Assay for Identification, Quantification, and Breakpoint Cluster Region Determination of t(9;22) Transcripts

t(9;22) generates the BCR-ABL fusion gene, the hallmark of chronic myeloid leukemia (CML) but also found in acute lymphoblastic leukemia (ALL). Multiple chimeric transcripts translate to proteins of 190 or 210 kd and, rarely, 230 kd. CML typically carries p210 BCR-ABL while ALL is most often associa...

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Detalhes bibliográficos
Main Authors: Gutiérrez, Marina I., Timson, Georgina, Siraj, Abdul K., Bu, Rong, Barbhaya, Shakuntala, Banavali, Sripad, Bhatia, Kishor
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867499/
https://ncbi.nlm.nih.gov/pubmed/15681473
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