Regulation of Joint Destruction and Inflammation by p53 in Collagen-Induced Arthritis

The role of the tumor suppressor p53 as a key regulator of inflammation was examined in murine collagen-induced arthritis (CIA), a model of rheumatoid arthritis. Wild-type DBA/1 mice develop progressive arthritis in this model, in which p53 expression and apoptosis are evident in the synovial cells....

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Main Authors: Yamanishi, Yuji, Boyle, David L., Pinkoski, Michael J., Mahboubi, Artin, Lin, Tesu, Han, Zuoning, Zvaifler, Nathan J., Green, Douglas R., Firestein, Gary S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Investigative Pathology 2002
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867134/
https://ncbi.nlm.nih.gov/pubmed/11786406
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