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Regional analysis of p53 mutations in rheumatoid arthritis synovium
The p53 tumor suppressor protein plays a central role in cell cycle regulation, DNA repair, and apoptosis. Recent studies indicate that DNA damage and somatic mutations in the p53 gene can occur because of genotoxic stress in many tissues, including the skin, colon, and synovium. Although somatic mu...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The National Academy of Sciences
2002
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC126618/ https://ncbi.nlm.nih.gov/pubmed/12119414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.152333199 |
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