p53 tumor suppressor gene mutations in fibroblast-like synoviocytes from erosion synovium and non-erosion synovium in rheumatoid arthritis

Abnormalities in the p53 tumor suppressor gene have been detected in rheumatoid arthritis (RA) and could contribute to the pathogenesis of chronic disease. To determine whether synoviocytes from invasive synovium in RA have an increased number of mutations compared with non-erosion synoviocytes, p53...

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Bibliographic Details
Main Authors: Yamanishi, Yuji, Boyle, David L, Green, Douglas R, Keystone, Edward C, Connor, Alison, Zollman, Susan, Firestein, Gary S
Format: Artigo
Language:Inglês
Published: BioMed Central 2005
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064878/
https://ncbi.nlm.nih.gov/pubmed/15642132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1448
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