p53 tumor suppressor gene mutations in fibroblast-like synoviocytes from erosion synovium and non-erosion synovium in rheumatoid arthritis

Abnormalities in the p53 tumor suppressor gene have been detected in rheumatoid arthritis (RA) and could contribute to the pathogenesis of chronic disease. To determine whether synoviocytes from invasive synovium in RA have an increased number of mutations compared with non-erosion synoviocytes, p53...

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Main Authors: Yamanishi, Yuji, Boyle, David L, Green, Douglas R, Keystone, Edward C, Connor, Alison, Zollman, Susan, Firestein, Gary S
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2005
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064878/
https://ncbi.nlm.nih.gov/pubmed/15642132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1448
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