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p53 tumor suppressor gene mutations in fibroblast-like synoviocytes from erosion synovium and non-erosion synovium in rheumatoid arthritis

Abnormalities in the p53 tumor suppressor gene have been detected in rheumatoid arthritis (RA) and could contribute to the pathogenesis of chronic disease. To determine whether synoviocytes from invasive synovium in RA have an increased number of mutations compared with non-erosion synoviocytes, p53...

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Bibliografiska uppgifter
Huvudupphovsmän: Yamanishi, Yuji, Boyle, David L, Green, Douglas R, Keystone, Edward C, Connor, Alison, Zollman, Susan, Firestein, Gary S
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2005
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064878/
https://ncbi.nlm.nih.gov/pubmed/15642132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1448
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