Activation of Rat Alveolar Macrophage-Derived Latent Transforming Growth Factor β-1 by Plasmin Requires Interaction with Thrombospondin-1 and its Cell Surface Receptor, CD36

Transforming growth factor-β-1 (TGF-β1) is secreted by cells in a latent form (L-TGF-β1) noncovalently bound to a latency-associated peptide. Activated alveolar macrophages obtained from rat lungs after bleomycin-induced pulmonary injury released increased amounts of active TGF-β1 as well as plasmin...

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Main Authors: Yehualaeshet, Teshome, O’Connor, Robert, Green-Johnson, Julia, Mai, Sabine, Silverstein/p, Roy, Murphy-Ullrich, Joanne E., Khalil, Nasreen
格式: Artigo
語言:Inglês
出版: American Society for Investigative Pathology 1999
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866879/
https://ncbi.nlm.nih.gov/pubmed/10487979
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