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Upregulation of myocellular DGAT1 augments triglyceride synthesis in skeletal muscle and protects against fat-induced insulin resistance

Increased fat deposition in skeletal muscle is associated with insulin resistance. However, exercise increases both intramyocellular fat stores and insulin sensitivity, a phenomenon referred to as “the athlete’s paradox”. In this study, we provide evidence that augmenting triglyceride synthesis in s...

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Detalhes bibliográficos
Main Authors: Liu, Li, Zhang, Yiying, Chen, Nancy, Shi, Xiaojing, Tsang, Bonny, Yu, Yi-Hao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866250/
https://ncbi.nlm.nih.gov/pubmed/17510710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30565
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