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Paradoxical Coupling of Triglyceride Synthesis and Fatty Acid Oxidation in Skeletal Muscle Overexpressing DGAT1

OBJECTIVE: Transgenic expression of diacylglycerol acyltransferase-1 (DGAT1) in skeletal muscle leads to protection against fat-induced insulin resistance despite accumulation of intramuscular triglyceride, a phenomenon similar to what is known as the “athlete paradox.” The primary objective of this...

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Detalhes bibliográficos
Main Authors: Liu, Li, Shi, Xiaojing, Choi, Cheol Soo, Shulman, Gerald I., Klaus, Katherine, Nair, K. Sreekumaran, Schwartz, Gary J., Zhang, Yiying, Goldberg, Ira J., Yu, Yi-Hao
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768165/
https://ncbi.nlm.nih.gov/pubmed/19675136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-1096
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