Structure and Function of Flavivirus NS5 Methyltransferase

The plus-strand RNA genome of flavivirus contains a 5′ terminal cap 1 structure (m(7)GpppAmG). The flaviviruses encode one methyltransferase, located at the N-terminal portion of the NS5 protein, to catalyze both guanine N-7 and ribose 2′-OH methylations during viral cap formation. Representative fl...

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Detalhes bibliográficos
Main Authors: Zhou, Yangsheng, Ray, Debashish, Zhao, Yiwei, Dong, Hongping, Ren, Suping, Li, Zhong, Guo, Yi, Bernard, Kristen A., Shi, Pei-Yong, Li, Hongmin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Structure and Assembly
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866096/
https://ncbi.nlm.nih.gov/pubmed/17267492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02704-06
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