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Structure and Function of Flavivirus NS5 Methyltransferase
The plus-strand RNA genome of flavivirus contains a 5′ terminal cap 1 structure (m(7)GpppAmG). The flaviviruses encode one methyltransferase, located at the N-terminal portion of the NS5 protein, to catalyze both guanine N-7 and ribose 2′-OH methylations during viral cap formation. Representative fl...
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| Main Authors: | , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology
2007
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1866096/ https://ncbi.nlm.nih.gov/pubmed/17267492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02704-06 |
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