Conserved Determinants for Membrane Association of Nonstructural Protein 5A from Hepatitis C Virus and Related Viruses

Nonstructural protein 5A (NS5A) is a membrane-associated essential component of the hepatitis C virus (HCV) replication complex. An N-terminal amphipathic alpha helix mediates in-plane membrane association of HCV NS5A and at the same time is likely involved in specific protein-protein interactions r...

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Main Authors: Brass, Volker, Pal, Zsuzsanna, Sapay, Nicolas, Deléage, Gilbert, Blum, Hubert E., Penin, François, Moradpour, Darius
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2007
Teme:
Genome Replication and Regulation of Viral Gene Expression
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866014/
https://ncbi.nlm.nih.gov/pubmed/17192310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01279-06
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