An Amphipathic α-Helix at the C Terminus of Hepatitis C Virus Nonstructural Protein 4B Mediates Membrane Association

Nonstructural protein 4B (NS4B) plays an essential role in the formation of the hepatitis C virus (HCV) replication complex. It is an integral membrane protein that has been only poorly characterized to date. It is believed to comprise a cytosolic N-terminal part, a central part harboring four trans...

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Hlavní autoři: Gouttenoire, Jérôme, Montserret, Roland, Kennel, Audrey, Penin, François, Moradpour, Darius
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
Témata:
Genome Replication and Regulation of Viral Gene Expression
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772773/
https://ncbi.nlm.nih.gov/pubmed/19692468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01122-09
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