Human Immunodeficiency Virus Type 1 Pathobiology Studied in Humanized BALB/c-Rag2(−/−)γ(c)(−/−) Mice

The specificity of human immunodeficiency virus type 1 (HIV-1) for human cells precludes virus infection in most mammalian species and limits the utility of small animal models for studies of disease pathogenesis, therapy, and vaccine development. One way to overcome this limitation is by human cell...

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Detalhes bibliográficos
Main Authors: Gorantla, Santhi, Sneller, Hannah, Walters, Lisa, Sharp, John G., Pirruccello, Samuel J., West, John T., Wood, Charles, Dewhurst, Stephen, Gendelman, Howard E., Poluektova, Larisa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865995/
https://ncbi.nlm.nih.gov/pubmed/17182671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02010-06
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