Human Immunodeficiency Virus Type 1 Pathobiology Studied in Humanized BALB/c-Rag2(−/−)γ(c)(−/−) Mice

The specificity of human immunodeficiency virus type 1 (HIV-1) for human cells precludes virus infection in most mammalian species and limits the utility of small animal models for studies of disease pathogenesis, therapy, and vaccine development. One way to overcome this limitation is by human cell...

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Bibliografiske detaljer
Main Authors: Gorantla, Santhi, Sneller, Hannah, Walters, Lisa, Sharp, John G., Pirruccello, Samuel J., West, John T., Wood, Charles, Dewhurst, Stephen, Gendelman, Howard E., Poluektova, Larisa
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2007
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865995/
https://ncbi.nlm.nih.gov/pubmed/17182671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02010-06
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