Human Dendritic Cells Transduced with Herpes Simplex Virus Amplicons Encoding Human Immunodeficiency Virus Type 1 (HIV-1) gp120 Elicit Adaptive Immune Responses from Human Cells Engrafted into NOD/SCID Mice and Confer Partial Protection against HIV-1 Challenge

Small-animal models are needed to test human immunodeficiency virus (HIV) vaccine efficacy following viral challenge. To this end, we examined HIV-1-specific immune responses following immunization of nonobese diabetic-severe combined immunodeficient mice that were repopulated with human peripheral...

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Detalhes bibliográficos
Main Authors: Gorantla, Santhi, Santos, Kathlyn, Meyer, VaKara, Dewhurst, Stephen, Bowers, William J., Federoff, Howard J., Gendelman, Howard E., Poluektova, Larisa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC546587/
https://ncbi.nlm.nih.gov/pubmed/15681415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.4.2124-2132.2005
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