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CD8+ cell depletion accelerates HIV-1 immunopathology in humanized mice
Stable engraftment of human lymphoid tissue in NOD/scid-IL-2Rγ(c)(null) mice after CD34(+) hematopoietic stem cell reconstitution permits the evaluation of ongoing HIV-1 infection for weeks to months. We demonstrate that HIV-1 infected rodents developed virus-specific cellular immune responses. CD8(...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3008566/ https://ncbi.nlm.nih.gov/pubmed/20495069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000438 |
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