CD8+ cell depletion accelerates HIV-1 immunopathology in humanized mice

Stable engraftment of human lymphoid tissue in NOD/scid-IL-2Rγ(c)(null) mice after CD34(+) hematopoietic stem cell reconstitution permits the evaluation of ongoing HIV-1 infection for weeks to months. We demonstrate that HIV-1 infected rodents developed virus-specific cellular immune responses. CD8(...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Gorantla, Santhi, Makarov, Edward, Finke-Dwyer, Jennifer, Gebhart, Catherine L., Domm, William, Dewhurst, Stephen, Gendelman, Howard E., Poluektova, Larisa Y.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008566/
https://ncbi.nlm.nih.gov/pubmed/20495069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000438
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker