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Nuclear Import of Bovine Papillomavirus Type 1 E1 Protein Is Mediated by Multiple Alpha Importins and Is Negatively Regulated by Phosphorylation near a Nuclear Localization Signal

Papillomavirus DNA replication occurs in the nucleus of infected cells and requires the viral E1 protein, which enters the nuclei of host epithelial cells and carries out enzymatic functions required for the initiation of viral DNA replication. In this study, we investigated the pathway and regulati...

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Bibliographic Details
Main Authors: Bian, Xue-Lin, Rosas-Acosta, Germán, Wu, Yu-Chieh, Wilson, Van G.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865984/
https://ncbi.nlm.nih.gov/pubmed/17192311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01850-06
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