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Nuclear Import of Bovine Papillomavirus Type 1 E1 Protein Is Mediated by Multiple Alpha Importins and Is Negatively Regulated by Phosphorylation near a Nuclear Localization Signal

Papillomavirus DNA replication occurs in the nucleus of infected cells and requires the viral E1 protein, which enters the nuclei of host epithelial cells and carries out enzymatic functions required for the initiation of viral DNA replication. In this study, we investigated the pathway and regulati...

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Detalhes bibliográficos
Main Authors: Bian, Xue-Lin, Rosas-Acosta, Germán, Wu, Yu-Chieh, Wilson, Van G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865984/
https://ncbi.nlm.nih.gov/pubmed/17192311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01850-06
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