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Effect of Farnesol on a Mouse Model of Systemic Candidiasis, Determined by Use of a DPP3 Knockout Mutant of Candida albicans

This work extends our previous observation that the fungus Candida albicans secretes micromolar levels of farnesol and that accumulation of farnesol in vitro prevents the yeast-to-mycelium conversion in a quorum-sensing manner. What does farnesol do in vivo? The purpose of this study was to determin...

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Detalhes bibliográficos
Main Authors: Navarathna, Dhammika H. M. L. P., Hornby, Jacob M., Krishnan, Navasona, Parkhurst, Anne, Duhamel, Gerald E., Nickerson, Kenneth W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865729/
https://ncbi.nlm.nih.gov/pubmed/17283095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01182-06
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