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Enhanced Production of Farnesol by Candida albicans Treated with Four Azoles

The dimorphic fungus Candida albicans excretes farnesol, which is produced enzymatically from the sterol biosynthetic intermediate farnesyl pyrophosphate. Inhibition of C. albicans by four azole antifungals, fluconazole, ketoconazole, miconazole, and clotrimazole, caused elevated farnesol production...

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Detalhes bibliográficos
Main Authors: Hornby, Jacob M., Nickerson, Kenneth W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC415631/
https://ncbi.nlm.nih.gov/pubmed/15155241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.6.2305-2307.2004
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