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Enhanced Production of Farnesol by Candida albicans Treated with Four Azoles

The dimorphic fungus Candida albicans excretes farnesol, which is produced enzymatically from the sterol biosynthetic intermediate farnesyl pyrophosphate. Inhibition of C. albicans by four azole antifungals, fluconazole, ketoconazole, miconazole, and clotrimazole, caused elevated farnesol production...

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Autores principales: Hornby, Jacob M., Nickerson, Kenneth W.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC415631/
https://ncbi.nlm.nih.gov/pubmed/15155241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.6.2305-2307.2004
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