Exogenous Farnesol Interferes with the Normal Progression of Cytokine Expression during Candidiasis in a Mouse Model

Candida albicans, a dimorphic fungus composed of yeast and mycelial forms, is the most common human fungal pathogen. Th1 cytokines such as interleukin-2 (IL-2), gamma interferon (IFN-γ), and tumor necrosis factor alpha (TNF-α), which are induced by macrophage IL-12, are critical to resistance agains...

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Главные авторы: Navarathna, Dhammika H. M. L. P., Nickerson, Kenneth W., Duhamel, Gerald E., Jerrels, Thomas R., Petro, Thomas M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2007
Предметы:
Fungal and Parasitic Infections
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951970/
https://ncbi.nlm.nih.gov/pubmed/17517874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00397-07
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